Christoffer Bundgaard Selected Research

3- bromo- 10- difluoromethyl- 9H- imidazo(1,5- a)(1,2,4)triazolo(1,5- d)(1,4)benzodiazepine

5/2013	RO4938581, a GABAAα5 modulator, displays strong CYP1A2 autoinduction properties in rats.
6/2012	Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats.

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Christoffer Bundgaard Research Topics

Disease

7	Cognitive Dysfunction 01/2018 - 06/2012
7	Schizophrenia (Dementia Praecox) 10/2015 - 08/2006
6	Alzheimer Disease (Alzheimer's Disease) 03/2023 - 06/2012
2	Catalepsy 08/2015 - 09/2014
2	Central Nervous System Diseases (CNS Diseases) 09/2014 - 09/2014
1	Migraine Disorders (Migraine) 05/2024
1	Dyskinesias (Dyskinesia) 01/2024
1	Parkinson Disease (Parkinson's Disease) 01/2024
1	Tauopathies 03/2023
1	Disease Progression 03/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2023
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Absence Epilepsy (Childhood Absence Epilepsy) 01/2021
1	Mania (Manias) 01/2021
1	Bipolar Disorder (Manic Depressive Psychosis) 01/2021
1	Seizures (Absence Seizure) 01/2021
1	Heart Failure 01/2021
1	Sleep Wake Disorders 01/2020
1	Major Depressive Disorder (Major Depressive Disorders) 01/2019
1	Nervous System Diseases (Neurological Disorders) 01/2018
1	Hyperekplexia 01/2017
1	Hypertension (High Blood Pressure) 01/2017
1	Alcoholism (Alcohol Abuse) 08/2015
1	Narcolepsy 08/2015
1	Mental Disorders (Mental Disorder) 09/2014
1	Psychotic Disorders (Schizoaffective Disorder) 03/2009

Drug/Important Bio-Agent (IBA)

4	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2018 - 08/2006
3	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2022 - 01/2017
3	Antipsychotic Agents (Antipsychotics)IBA 01/2021 - 09/2014
3	brexpiprazoleIBA 10/2015 - 09/2014
3	Phencyclidine (Angel Dust)IBA 08/2015 - 03/2009
2	VortioxetineIBA 01/2019 - 01/2018
2	serotonin 6 receptorIBA 01/2017 - 01/2016
2	Dopamine (Intropin)FDA LinkGeneric 09/2014 - 03/2009
2	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 09/2014 - 08/2014
2	3- bromo- 10- difluoromethyl- 9H- imidazo(1,5- a)(1,2,4)triazolo(1,5- d)(1,4)benzodiazepineIBA 05/2013 - 06/2012
1	Tryptamines (Triptans)IBA 05/2024
1	Levodopa (L Dopa)FDA LinkGeneric 01/2024
1	Amantadine (Aman)FDA LinkGeneric 01/2024
1	5- methyl- N- (4- methylpyrimidin- 2- yl)- 4- (1H- pyrazol- 4- yl)thiazol- 2- amineIBA 01/2024
1	metabotropic glutamate receptor 4IBA 01/2024
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2024
1	N1- (3,4- dichlorophenyl)- cyclohexane- 1,2- dicarboxamideIBA 01/2024
1	tau Proteins (tau Protein)IBA 03/2023
1	Biomarkers (Surrogate Marker)IBA 03/2023
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	Acetylcholine (Acetylcholine Chloride)FDA Link 11/2021
1	AcetylcholinesteraseIBA 11/2021
1	Muscarinic M1 ReceptorIBA 11/2021
1	Cholinergic Agents (Cholinergics)IBA 11/2021
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2021
1	Cyclic NucleotidesIBA 01/2021
1	IvabradineIBA 01/2021
1	asenapine FDA Link 01/2021
1	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2021
1	ElacridarIBA 01/2021
1	Cyclic Nucleotide-Gated Cation ChannelsIBA 01/2021
1	Cysteine Loop Ligand-Gated Ion Channel ReceptorsIBA 01/2020
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	Ionotropic Glutamate ReceptorsIBA 01/2018
1	LigandsIBA 01/2018
1	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2018
1	Vasodilator Agents (Vasodilators)IBA 01/2017
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2016
1	Lu AF33241IBA 08/2015
1	AcidsIBA 08/2015
1	Illicit Drugs (Recreational Drugs)IBA 08/2015
1	Serotonin (5 Hydroxytryptamine)IBA 09/2014
1	Aripiprazole (Abilify)FDA Link 09/2014
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 09/2014
1	Lu AF64280IBA 08/2014
1	BenzodiazepinesIBA 05/2013
1	Aminobutyrates (Aminobutyric Acid)IBA 06/2012
1	Memantine (Namenda)FDA Link 06/2012
1	gamma-Aminobutyric Acid (GABA)IBA 06/2012
1	ezogabine (retigabine)IBA 03/2009
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 08/2006

Therapy/Procedure

3	Therapeutics 11/2021 - 10/2015
1	Oral Administration 01/2021